We study the impact of virus infection on cell function and tissue integrity in the respiratory tract, nervous system, and at maternal-fetal interface. Our work focuses on endemic and emerging viruses, both representing a significant threat to global health. We apply multidisciplinary approaches comprising elements of cell biology, immunology, and virology. With the objective of understanding the pathophysiological mechanisms of infection and identifying therapeutic targets, we apply animal models and advanced in vitro systems such as primary cell cultures, tissue explants, and organoids.
